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Tag #python

Agno

Agno

Agno

High-performance framework and runtime (AgentOS) for multi-agent systems

v3.0.102026-09-16PythonApache-2.0
42.3k Open source Free tier Paid
AutoGen

AutoGen

Microsoft

Microsoft's multi-agent conversation framework (maintenance-only; new work moved to Microsoft Agent Framework)

Maintenance onlyNo updates in 6+ monthspython-v0.7.52025-09-30PythonMIT
61.1k Completely free Open source
Browser Use

Browser Use

Browser Use

Let an LLM agent drive a real browser — navigate, click, type, and extract from any website.

v0.13.102026-09-04PythonMIT
115.9k Open source Free tier Paid
Chroma

Chroma

Chroma

Open-source embedding database for RAG — store vectors and query by similarity in a few lines.

v1.5.92026-05-05PythonApache-2.0
29.4k Open source Free tier Paid
CrewAI

CrewAI

CrewAI

Role-based multi-agent orchestration — assemble a crew of agents with goals and tasks.

v1.15.222026-09-16PythonMIT
58.9k Open source Free tier Paid
DeepEval

DeepEval

Confident AI

Open-source "Pytest for LLMs" — unit-test your model and RAG output with metrics.

python-v4.2.02026-08-24PythonApache-2.0
18.4k Open source Free tier Paid
DSPy

DSPy

Stanford NLP

Program — don't prompt — language models; declare modules and let DSPy compile and optimize the prompts.

v3.3.12026-08-21PythonMIT
38.2k Completely free Open source
E2B

E2B

E2B

Secure, isolated cloud sandboxes that let AI agents run model-generated code safely

e2b@2.51.02026-09-18PythonApache-2.0
13.9k Open source Free tier Paid
Guardrails AI

Guardrails AI

Guardrails AI

Validate and structure LLM input/output with composable validators from the Guardrails Hub.

v0.11.02026-08-14PythonApache-2.0
7.4k Open source Paid

instructor

567 Labs

Structured, validated outputs from any LLM — define a Pydantic model and get a typed object back.

v1.17.02026-09-09PythonMIT
13.9k Completely free Open source
LangChain

LangChain

LangChain

The original LLM-app framework — standard model/tool interfaces, hundreds of integrations, and the create_agent prebuilt that compiles to a LangGraph agent

langchain-core==1.6.42026-09-21Python / JSMIT
146.8k Completely free Open source
LangGraph

LangGraph

LangChain

Graph-based orchestration for stateful, multi-step agents with branching, loops, and human-in-the-loop

v1.2.122026-09-21Python / JSMIT
42.1k Open source Free tier Paid

LiteLLM

BerriAI

Call 100+ LLM APIs through one OpenAI-style interface, plus a proxy with routing, fallbacks, and cost tracking.

v1.101.02026-09-15PythonMIT
59.4k Open source Paid

Realtime framework for voice, video, and physical AI agents on the LiveKit WebRTC stack

livekit-agents@1.8.22026-09-15PythonApache-2.0
14.3k Open source Free tier Paid
LlamaIndex

LlamaIndex

LlamaIndex

Data framework for building RAG pipelines and document agents over your own data

v0.14.252026-09-21PythonMIT
52.3k Open source Free tier Paid

Mem0

Mem0

Memory layer for agents — extracts and recalls facts across sessions, not raw chat logs.

openclaw-v1.2.02026-09-18PythonApache-2.0
65.8k Open source Free tier Paid
mini-SWE-agent

mini-SWE-agent

Princeton NLP

The minimal successor to SWE-agent — a ~100-line core that autonomously resolves GitHub issues, as performant but far simpler

v2.4.62026-07-23PythonMIT
7.9k Completely free Open source

Modal

Modal Labs

Serverless cloud runtime whose Sandboxes run untrusted, model-generated code in isolated containers on demand

v1.3.12026-01-22PythonApache-2.0
515 Free tier Paid

Programmable rails for LLM apps — keep conversations safe, on-topic, and on-policy with Colang flows.

v0.24.12026-09-16PythonApache-2.0
7.2k Completely free Open source

OpenAI's lightweight SDK for agents with tools, handoffs, and guardrails

v0.22.32026-09-17PythonMIT
29.6k Completely free Open source
OpenHands

OpenHands

All Hands AI

Open-source platform for autonomous AI software developers that edit code, run commands, and browse the web

v1.21.02026-09-22PythonMIT
88.8k Open source Free tier Paid
Opik

Opik

Comet

Comet's open-source platform for tracing, evaluating, and monitoring LLM apps

v2.2.742026-09-22PythonApache-2.0
22.2k Open source Free tier Paid
Pipecat

Pipecat

Daily

Open-source Python framework for real-time voice and multimodal conversational agents

v1.11.02026-09-18PythonBSD-2-Clause
15.8k Open source Free tier Paid
Pydantic AI

Pydantic AI

Pydantic

Type-safe agent framework from the Pydantic team — structured, validated results with any model

v2.47.02026-09-22PythonMIT
20.1k Completely free Open source
Ragas

Ragas

Exploding Gradients

Open-source evaluation framework for RAG pipelines and LLM applications

No updates in 6+ monthsv0.4.32026-01-13PythonApache-2.0
15.8k Completely free Open source

Run embedding models locally (e.g. bge-m3) to turn text into vectors for RAG and memory — no API.

v6.1.02026-09-18PythonApache-2.0
19.1k Completely free Open source
smolagents

smolagents

Hugging Face

Hugging Face's minimal library for agents that act by writing and running code

v1.26.02026-05-29PythonApache-2.0
29.4k Completely free Open source
SWE-agent

SWE-agent

Princeton NLP

Princeton's agent that autonomously resolves real GitHub issues via an agent–computer interface. Now maintenance-only — superseded by mini-SWE-agent

Maintenance onlyNo updates in 1+ yearv1.1.02025-05-22PythonMIT
20.4k Completely free Open source
vLLM

vLLM

PyTorch Foundation

High-throughput serving engine for running open LLMs with an OpenAI-compatible API

v0.30.02026-09-22PythonApache-2.0
92.4k Completely free Open source
Zep

Zep

Zep

Long-term memory layer for agents, building a temporal knowledge graph from conversations

zep-ingest-v0.3.02026-08-28PythonApache-2.0
4.9k Open source Free tier Paid